Forensic anthropologist Dr. Temperance Brennan is confused as to how she got where she is. Somehow, Brennan is badly injured and tied securely in what appears to be an underground tomb. As she regains her senses, slowly flashes of what happened to her begin to appear in her mind. Based on an anonymous tip to authorities, Brennan arrived in Chicago with Andrew Ryan of the Serete du Quebec where she is being accused of erring in her autopsy of Canadian heiress Rose Jurmain. Meanwhile back in her Montreal lab, Brennan links Jurmain's death to the brutal murders of other elderly women by a particularly nasty serial killer. As she explores her premise further, she is just beginning to understand she is a trapped rodent in a deadly cat and mouse game. This is a super thriller that contains several strong subplots; especially intriguing is the challenge to the heroine's competency from an unknown source who seems to know forensics. Much more personal than usual, the courageous Dr. Brennan feels like a hunted animal who though wounded goes after her predator.